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Creators/Authors contains: "Larson, C."

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  1. Schaeffer, J; Novogrodsky, R; Perovic, A; Prévost, P; Tuller, L (Ed.)
    Alongside the behavioral features of autism, this neurodevelopmental disorder is characterized by important differences in the neural circuitry underlying language processing. Regarding brain structure, most neurotypical individuals have larger left-hemisphere volumes of brain regions that are important for language, compared to the same regions in the right hemisphere (the right half of the brain). This asymmetry is due to neural specialization of left hemisphere regions for the purpose of language functions. In contrast, the brains of autistic individuals seem to be more symmetrical, suggesting that language difficulties are associated with reduced left hemisphere specialization for language in the brain. The activity of brain regions involved in language also differs in autism. Examining brain activity reveals nuanced and important differences in the processes underlying language production and comprehension in neurotypical and autistic individuals, even when their language behavior appears similar. 
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    Free, publicly-accessible full text available August 1, 2026
  2. Although theory of mind (ToM) is seen as a primary contributor to pragmatic language use in autistic individuals, less work has considered the influence of structural language. This study examines grammaticality judgements, ToM (Reading the Eyes in the Mind, Social Attribution Test), and pragmatic language (a de novo measure based on Pragmatic Language Scales), and their associations, in three groups with heterogenous abilities: Current autism (n = 36); those with a history of autism spectrum disorder, who no longer display symptoms ( “loss of autism diagnosis”, LAD; n = 32), and non-autistic (n = 36) adolescents and adults with fluent verbal skills. Results showed pragmatic difficulties in autism, relative to both other groups, difficulties in affective ToM relative to both other groups, and difficulties in structural language relative to neurotypical controls; LAD individuals showed no impairments. While pairwise associations of structural language and matrix reasoning with pragmatic language were observed, ToM was the only unique predictor of pragmatic language when all measures were included in the models. Results suggest complex interactions among pragmatic and structural language, and ToM, and that pragmatic language improves meaningfully with broad changes in broad aspects of autism when individuals lose the autism diagnosis. 
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    Free, publicly-accessible full text available August 1, 2026
  3. Cook, S; Katz, B; Moore-Russo, D (Ed.)
    Free, publicly-accessible full text available December 13, 2025
  4. Background: "Frank autism," recognizable through the first minutes of an interaction, describes a behavioral presentation of a subset of autistic individuals that is closely tied to social communication challenges, and may be linked to so-called "prototypical autism." To date, there is no research on frank autism presentations of autistic adolescents and young adults, nor individuals diagnosed with autism spectrum disorder (ASD) in childhood who do not meet diagnostic criteria during or after adolescence (loss of autism diagnosis, LAD). In addition, there are currently no data on the factors that drive frank autism impressions in these adolescent groups. Methods: This study quantifies initial impressions of autistic characteristics in 24 autistic, 24 LAD and 26 neurotypical (NT) individuals ages 12 to 39 years. Graduate student and expert clinicians completed five-minute impressions, rated confidence in their own impressions, and scored the atypicality of behaviors associated with impressions; impressions were compared with current gold-standard diagnostic outcomes. Results: Overall, clinicians' impressions within the first five minutes generally matched current gold-standard diagnostic status (clinical best estimate), were highly correlated with ADOS-2 CSS, and were driven primarily by prosodic and facial cues. However, this brief observation did not detect autism in all cases. While clinicians noted some subclinical atypicalities in the LAD group, impressions of the LAD and NT groups were similar. Limitations: The brief observations in this study were conducted during clinical research, including some semi-structured assessments. While results suggest overall concordance between initial impressions and diagnoses following more thorough evaluation, findings may not generalize to less structured, informal contexts. In addition, our sample was demographically homogeneous and comprised only speaking autistic participants. They were also unmatched for sex, with more females in the non-autistic group. Future studies should recruit samples that are diverse in demographic variables and ability level to replicate these findings and explore their implications. Conclusions: Results provide insights into the behavioral characteristics that contribute to the diagnosis of adolescents and young adults and may help inform diagnostic decision making in the wake of an increase in the demand for autism evaluations later than childhood. They also substantiate claims of an absence of apparent autistic characteristics in individuals who have lost the diagnosis. 
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  5. S. S. Karunakaran; A. Higgins (Ed.)
    Vector spaces are often taught with an axiomatic focus, but this has been shown to rely on knowledge many students have not yet developed. In this paper, we examine two students’ conceptual resources for reasoning about null spaces drawing on data from a paired teaching experiment. The task sequence is set in the context of a school with one directional hallways. Students’ informal reasoning about paths that leave the room populations unchanged supported more formal reasoning about null spaces. We found that one student used context-based resources (such as ‘loops’ in hallway) to reason about null spaces, while the other student drew largely on previously formalized mathematical resources (e.g. free variables, linear dependence). The use of formal resources sometimes required recontextualization, which may function to constrain student sense-making or afford opportunities for broadening students’ formal prior knowledge. 
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  6. Abstract Quantum error correction can preserve quantum information in the presence of local errors, but correlated errors are fatal. For superconducting qubits, high-energy particle impacts from background radioactivity produce energetic phonons that travel throughout the substrate and create excitations above the superconducting ground state, known as quasiparticles, which can poison all qubits on the chip. We use normal metal reservoirs on the chip back side to downconvert phonons to low energies where they can no longer poison qubits. We introduce a pump-probe scheme involving controlled injection of pair-breaking phonons into the qubit chips. We examine quasiparticle poisoning on chips with and without back-side metallization and demonstrate a reduction in the flux of pair-breaking phonons by over a factor of 20. We use a Ramsey interferometer scheme to simultaneously monitor quasiparticle parity on three qubits for each chip and observe a two-order of magnitude reduction in correlated poisoning due to background radiation. 
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  7. Karunakaran, S.; Higgins, A. (Ed.)
    Social Network Analysis is a method to analyze individuals’ social accessibility and power. We adapt it to change inequitable issues in STEM postsecondary education. Equity issues in mathematics education, such as underrepresented women and racial disparities, are prevalent. With the social capital perspective, we investigate the demographic characteristics of influential students and their social networks. Seventeen participants are undergraduate students in an inquiry-oriented linear algebra course. The number of nominations on discussion boards as “Shout-out” is data to measure influence and map the social network. By analyzing data with UCINET, we found that (1) the most influential students are non-White males and the principal components of the network are male-dominant, and (2) there is a female-dominant small cluster and female students have reciprocal networks. This study suggests further discussions of (1) how discussion boards position students with the social capital perspective and (2) intersectionality, especially for women of color. 
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  8. Karunakaran, S.; & Higgins, A. (Ed.)
    Systems of equations is a core topic in linear algebra courses. Solving systems with no or infinitely many solutions tends to be less intuitive for students. In this study, we examined two students’ reasoning about the relationship between the structure of a system of linear equations and its solution set, particularly when creating systems with a certain number of equations and unknowns. Using data from a paired teaching experiment, we found that both students favored the notion of parallel planes, both geometrically and numerically, in the case of a system having no solution or infinitely many solutions. We also found that algebraic or numerical approaches were used as the main way of developing systems with a unique solution, especially in systems with more than two equations and two unknowns. In particular, one student gravitated toward geometric approaches and the other toward algebraic and numerical approaches. 
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  9. Karunakaran, S. S.; Higgins, A. (Ed.)
    Systems of equations is a core topic in linear algebra courses. Solving systems with no or infinitely many solutions tends to be less intuitive for students. In this study, we examined two students’ reasoning about the relationship between the structure of a system of linear equations and its solution set, particularly when creating systems with a certain number of equations and unknowns. Using data from a paired teaching experiment, we found that both students favored the notion of parallel planes, both geometrically and numerically, in the case of a system having no solution or infinitely many solutions. We also found that algebraic or numerical approaches were used as the main way of developing systems with a unique solution, especially in systems with more than two equations and two unknowns. In particular, one student gravitated toward geometric approaches and the other toward algebraic and numerical approaches. 
    more » « less
  10. Karunakaran, S. S.; Higgins, A. (Ed.)
    Vector spaces are often taught with an axiomatic focus, but this has been shown to rely on knowledge many students have not yet developed. In this paper, we examine two students’ conceptual resources for reasoning about null spaces drawing on data from a paired teaching experiment. The task sequence is set in the context of a school with one directional hallways. Students’ informal reasoning about paths that leave the room populations unchanged supported more formal reasoning about null spaces. We found that one student used context-based resources (such as ‘loops’ in hallway) to reason about null spaces, while the other student drew largely on previously formalized mathematical resources (e.g. free variables, linear dependence). The use of formal resources sometimes required recontextualization, which may function to constrain student sense-making or afford opportunities for broadening students’ formal prior knowledge. 
    more » « less